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SKU 99IEXQ42GC-----D

Sartobind® Q strong ion exchangers are perfect tools for the polishing of monoclonal antibodies for the removal of viruses, DNA, host cell proteins, leached Protein A, and endotoxins. As size exclusion effects are neglectible, they are suited for purification of viruses such as adeno or lentiviruses displaying one order of magnitude higher dynamic binding capacity. Sartobind® Q membrane adsorbers display a macro-porous structure with pore size of > 3 µm. Quaternary ammonium ligands are bound covalently to the complete internal surface of the membrane, resulting in separation media of high binding capacity combined with exceptional high flow rates. Applications virus and VLP capture: As size exclusion effects are negligible, they are suited for purification of viruses and display one order of magnitude higher dynamic binding capacity compared to resin. Viruses such as adeno- or lentiviruses are captured at high flow rates. The material allows also >100 cycles of re-use without loss of binding capacity. Benefits capture: · High speed purification at 5 - 30 bed volumes per minute · No size exclusion effects for large proteins an viruses / VLPs · >10fold higher binding capacities compared to conventional resins Applications flow-through polishing: Sartobind Q is the perfect tool for the flow-through polishing of valuable proteins such as monoclonal antibodies. The bed volumes can be kept sufficiently small during the removal of viruses, DNA, host cell proteins, leached Protein A, and endotoxins from such pharmaceutical proteins. Benefits flow-through polishing: · Virus clearance > 6 log · DNA below detection limit · Host cell protein removal > 99 % · Endotoxin removal > 5 log · Save 80 % of column costs Easy to use: · Plug and play devices from 0.08 mL to 5 L · Can be used like a filter · Flow rate up to 30 bed volumes/min · Re-usable or disposable

Specifications

Specifications

Documents

Brochure-Sartobind-SL.pdf

Sartobind® Membrane Chromatography

EN | 3,661 MB

Download

Flyer-Sartobind-Selection-Guide.pdf

Sartobind® Selection Guide

EN | 1,012 MB

Download

Data-Sartobind-96-well-plates.pdf

Sartobind® 96-well plates Datasheet

EN | 843,163 KB

Download

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Contact

Nova Natura UAB

Chemijos G. 11, LT-51347,
Kaunas, Lithuania

nova@novabio.lt
Phone: +370 (620) 70159

Reg No 305063819

Nova Natura OÜ

Kanali tee 6, 10112,
Tallinn, Estonia

nova@novabio.ee
Phone: +372 5656 0050

Reg No 14758203

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